UNITED STATES PHARMACOPEIAL CONVENTION INC -- DEXAMETHASONE -- 6505-00F036965
===================== Product Identification ===================== Product ID:DEXAMETHASONE MSDS Date:12/14/1987 FSC:6505 NIIN:00F036965 === Responsible Party === Company Name:UNITED STATES PHARMACOPEIAL CONVENTION INC Address:12601 TWINBROOK PKWY City:ROCKVILLE State:MD ZIP:20852-1717 Country:US Info Phone Num:301-881-0666 Emergency Phone Num:301-881-0666 Preparer's Name:WILLIAM M HELLER CAGE:14128 === Contractor Identification === Company Name:UNITED STATES PHARMACOPEIAL CONVENTION INC Address:12601 TWINBROOK PKWY Box:City:ROCKVILLE State:MD ZIP:20852-1717 Country:US Phone:301-881-0666 CAGE:14128 ============= Composition/Information on Ingredients ============= Ingred Name:PREGNA-1,4-DIENE-3,20-DIONE,9-FLUORO-11-BETA,17,21-TRIHYDROXY- 16-ALPHA-METHYL- *94-3* CAS:50-02-2 RTECS #:TU3980000 Ingred Name:DEXAMETHASONE PHOSPHATE *94-3* CAS:312-93-6 RTECS #:TU4055000 Ingred Name:DEXAMETHASONE SODIUM PHOSPHATE CAS:2392-39-4 RTECS #:TU4056000 Ingred Name:DEXAMETHASONE ACETATE *94-3* CAS:1177-87-3 RTECS #:TU4050000 ===================== Hazards Identification ===================== LD50 LC50 Mixture:ORAL LD50 (MOUSE): 1800 MG/KG Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO Health Hazards Acute and Chronic:POSSIBLE ALLERGIC REACTION TO DUST IF INHALED/INGESTED/CONTACT W/SKIN. EYE/SKIN/RESPIRATORY TRACT IRRITATION. POSSIBLE HYPERSENSITIZATION. IRRITATING TO MUCOUS MEMBRANES & RESPIRATORY TRACT. SUPPRESSI ON OF ADRENAL GLAND SECRETION & CUSHING'S SYNDROME. Explanation of Carcinogenicity:NONE Effects of Overexposure:PAIN, REDNESS, PUS-CONTAINING BLISTERS, IRRITATION, BURNING, ITCHING, PEELING, WATER RETENTION, ELECTROLYTE IMBALANCE, HYPERGLYCEMIA Medical Cond Aggravated by Exposure:HYPERSENSITIVITY TO MATERIAL, SYSTEMIC FUNGAL INFECTIONS ======================= First Aid Measures ======================= First Aid:INHALATION: REMOVE TO FRESH AIR. EYES/SKIN: FLUSH W/COPIOUS AMOUNTS OF WATER. INGESTION: FLUSH MOUTH W/WATER. OBTAIN MEDICAL ATTENTION IN ALL CASES. ===================== Fire Fighting Measures ===================== Extinguishing Media:WATER SPRAY, DRY CHEMICAL, CO2, FOAM AS APPROPRIATE FOR SURROUNDING FIRE/MATERIALS. Fire Fighting Procedures:EVACUATE AREA. WEAR SELF CONTAINED BREATHING APPARATUS & PROTECTIVE CLOTHING. Unusual Fire/Explosion Hazard:MATERIAL IS ASSUMED TO BE COMBUSTIBLE. AS W/ALL DRY POWDERS IT'S ADVISABLE TO GROUND MECHANICAL EQUIPMENT IN CONTACT W/DRY MATERIAL TO DISSIPATE STATIC. ================== Accidental Release Measures ================== Spill Release Procedures:WEAR APPROVED RESPIRATOR & CHEMICALLY COMPATIBLE GLOVES. VACUUM/SWEEP UP. AVOID DUST. PLACE MATERIAL IN APPROPRIATE CONTAINER FOR WASTE DISPOSAL. ====================== Handling and Storage ====================== Handling and Storage Precautions:STORE IN TIGHT CONTAINER. SHOULD BE HANDLED/STORED PER LABEL/OTHER INSTRUCTIONS TO ENSURE PRODUCT INTEGRITY. USE W/ADEQUATE VENTILATION. Other Precautions:AVOID CONTACT W/EYES/SKIN/CLOTHING. AVOID BREATHING DUST/MIST/FUMES/VAPORS. USE W/ADEQUATE DUST CONTROL. DON'T PERMIT EATING/DRINKING/SMOKING NEAR MATERIAL. PRODUCT SOLD AS REFERENCE STANDARD FOR CHEM ICAL ANALYSIS-NOT FOR HUMAN CONSUMPTION. ============= Exposure Controls/Personal Protection ============= Respiratory Protection:WEAR NIOSH APPROVED RESPIRATOR. Ventilation:ADEQUATE. LOCAL EXHAUST/MECHANICAL (GENERAL): RECOMMENDED. Protective Gloves:RUBBER Eye Protection:SAFETY GOGGLES Other Protective Equipment:APPROPRIATE LABORATORY APPAREL Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING BEFORE REUSE. WASH THOROUGHLY AFTER HANDLING. Supplemental Safety and Health INDIVIDUALS WORKING W/CHEMICALS SHOULD CONSIDER ALL CHEMICALS TO BE POTENTIALLY HAZARDOUS EVEN IF THEIR INDIVIDUAL HAZARDS MAY BE UNCHARACTERIZED/UNKNOWN. ================== Physical/Chemical Properties ================== Solubility in Water:INSOLUBLE Appearance and Odor:WHITE TO PRACTICALLY WHITE CRYSTALLINE POWDER W/NO ODOR ================= Stability and Reactivity Data ================= Stability Indicator/Materials to Avoid:YES Hazardous Decomposition Products:TOXIC FUMES ==================== Disposal Considerations ==================== Waste Disposal Methods:DISPOSE OF IAW/FEDERAL, STATE & LOCAL REGULATIONS. Disclaimer (provided with this information by the compiling agencies): This information is formulated for use by elements of the Department of Defense. The United States of America in no manner whatsoever, expressly or implied, warrants this information to be accurate and disclaims all liability for its use. Any person utilizing this document should seek competent professional advice to verify and assume responsibility for the suitability of this information to their particular situation.